Figure 2
From: Cytokines in chronic rheumatic diseases: is everything lack of homeostatic balance?
Schematic representation of agonists and antagonists determining the biological activities of IL-1 and TNF. icIL-1Ra, intracellular IL-1 receptor antagonist; SIGIRR, single immunoglobulin IL-1-related receptor; sIL-1Ra, soluble IL-1 receptor antagonist; sIL-1R, soluble IL-1 receptor; sTNF, soluble TNF; sTNFR, soluble TNF receptor.