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  1. To characterize the clinical and myo-fascial histopathological features, along with long-term treatment outcomes of patients with eosinophilic fasciitis (EF).

    Authors: Xiaoyuan Wang, Lining Zhang, Ying Hou, Tingjun Dai, Xiaotian Ma, Kai Shao, Chuanzhu Yan and Bing Zhao
    Citation: Arthritis Research & Therapy 2025 27:110
  2. Osteoarthritis (OA) is a highly prevalent and disabling condition lacking curative treatments, with only symptomatic relief available. Recognizing OA as a heterogenous disorder with diverse aetiologies and mol...

    Authors: Eva Reihs, Anita Fischer, Iris Gerner, Reinhard Windhager, Stefan Toegel, Frank Zaucke, Mario Rothbauer and Florien Jenner
    Citation: Arthritis Research & Therapy 2025 27:109
  3. Risk of cardiovascular events may increase after herpes zoster; therefore, American College of Rheumatology guidelines strongly recommend vaccination against herpes zoster in patients aged ≥ 18 years with rheu...

    Authors: Jeffrey R. Curtis, Danielle M. Conrad, Whitney S. Krueger, Andrew P. Gara and Kevin L. Winthrop
    Citation: Arthritis Research & Therapy 2025 27:108
  4. Microvascular dysfunction is considered one of the main pathogenetic pathways in systemic sclerosis (SSc), and endothelial cells plays a pivotal role even in the early phases of the disease. Endothelial dysfun...

    Authors: Giulia Bandini, Silvia Bellando Randone, Mirko Manetti, Lorenzo Dagna, Marco Matucci Cerinic and Alberto Moggi Pignone
    Citation: Arthritis Research & Therapy 2025 27:107
  5. Given the potential role of vagus nerve stimulation in treating rheumatoid arthritis (RA), we examined the incidence of RA and osteoarthritis (OA) in patients who underwent different forms of vagotomy that dis...

    Authors: Matthew C. Baker, Dávid Nagy, Suzanne Tamang, Erzsébet Horváth-Puhó and Henrik Toft Sørensen
    Citation: Arthritis Research & Therapy 2025 27:106
  6. Meniscus degeneration contributes to knee arthritis progression, but the cellular and molecular mechanisms of meniscus aging remain poorly understood. We aimed to characterize age-related changes in the rat me...

    Authors: Jing-Yi Wang, Yao-Hui Liu, Xiao Wang, Min Ma, Zhang-Yi Pan, Ao-Yuan Fan, Lai-Ya Lu, Zheng Liu, Kun Tao and Feng Yin
    Citation: Arthritis Research & Therapy 2025 27:105
  7. Synovitis, among the most common signs of early-stage osteoarthritis (OA), is mainly mediated by fibroblast-like synoviocytes (FLSs). Cartilage destruction creates chondrocyte lysates (CLs) that activate synov...

    Authors: Xue Du, Ruonan Liu, Zongrui Jiang, Chengyun Zhang, Zhijian Yang, Shu Hu and Zhiqi Zhang
    Citation: Arthritis Research & Therapy 2025 27:104
  8. Rheumatoid arthritis (RA) is a chronic systemic inflammatory autoimmune disease that can lead to progressive joint damage and irreversible disability when inadequately treated. RA is more common in women than ...

    Authors: Paloma Vela-Casasempere, Lucía Otero-Varela, Silvia Gómez Sabater, Rocío Caño Alameda, Cristina Campos Fernández, Jerusalén Calvo-Gutiérrez, Yanira Pérez-Vera, Sara Manrique Arija, Sagrario Bustabad, Javier Manero Ruiz, María Dolores Ruiz Montesino, Lucía Ruíz Gutiérrez, Antonio Mera Varela, Manuel José Moreno Ramos, Fernando Sánchez-Alonso and Isabel Castrejón
    Citation: Arthritis Research & Therapy 2025 27:103
  9. Chimeric antigen receptor (CAR) T-cell therapy targeting B cells has shown promising results, including drug-free remission, in adult-onset autoimmune diseases. Extending this therapeutic approach to the pedia...

    Authors: Maurine Jouret, Sebastien Viel, Benjamin Fournier, Sarah Benezech, Jérome Avouac, Marc Scherlinger and Alexandre Belot
    Citation: Arthritis Research & Therapy 2025 27:102
  10. Rheumatoid arthritis (RA) is an autoimmune disease characterized by the presence of autoantibodies against modified proteins, known as anti-modified protein autoantibodies (AMPAs). While the relationship betwe...

    Authors: Tineke J. van Wesemael, Fraser R. Morton, Judith W. Heutz, Marc P. Maurits, Annemarie L. Dorjée, Duncan Porter, Tom W. J. Huizinga, Karim Raza, Rene E. M. Toes, Rachel Knevel, Pascal H. P. de Jong, Anna Svärd and Diane van der Woude
    Citation: Arthritis Research & Therapy 2025 27:101
  11. Metabolic Syndrome (MetS), as a syndrome characterized by low-grade inflammation and energy metabolism disorders, is considered to be an important systemic risk factor for knee osteoarthritis (KOA). Our previo...

    Authors: Lu Ding, Jin-Yi Ren, Yi-Fan Huang, Jian-Zeng Zhang, Zi-Ran Bai, Yi Leng, Jun-Wei Tian, Jing Wei, Min-Li Jin, Guan Wang, Xia Li and Xin Qi
    Citation: Arthritis Research & Therapy 2025 27:99
  12. No established markers can effectively phenotype knee osteoarthritis (OA) patients into subgroups. Infrapatellar fat pad (IPFP) morphology data that can forecast disease symptoms, structural changes, and knee ...

    Authors: Jean-Pierre Pelletier, Patrice Paiement, François Abram, Marc Dorais, Jean-Pierre Raynauld and Johanne Martel-Pelletier
    Citation: Arthritis Research & Therapy 2025 27:98
  13. Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by synovial inflammation, hyperplasia, and joint destruction. Fibroblast-like synoviocytes (FLSs) are key effector cells in RA, contribu...

    Authors: Haoran Kong, Yushuang Qiao, Dahu Qi, Shixin Zhao, Zhiming Cao, Junhao Feng, Yitong Li, Yunke Liu and Tao Liu
    Citation: Arthritis Research & Therapy 2025 27:97
  14. Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by chronic inflammation and multi-organ damage. A central factor in SLE pathogenesis is the excessive production of type I inte...

    Authors: Jimin Zhang, Wuwei Zhuang, Yan Li, Chaoqiong Deng, Jingxiu Xuan, Yuechi Sun and Yan He
    Citation: Arthritis Research & Therapy 2025 27:96
  15. IgA vasculitis nephritis (IgAVN) manifests in up to 84% of adult patients with IgA vasculitis (IgAV) and is associated with an elevated risk of progression to chronic kidney failure. The underlying pathogenic ...

    Authors: Matija Bajželj, Emanuela Senjor, Nika Boštic, Matjaž Hladnik, Snežna Sodin-Šemrl, Milica Perišić Nanut, Janko Kos, Alojz Ihan, Alojzija Hočevar, Andreja Nataša Kopitar and Katja Lakota
    Citation: Arthritis Research & Therapy 2025 27:95
  16. Lymph node (LN) studies in anti-cyclic citrullinated protein antibodies (ACPA) positive rheumatoid arthritis (RA) patients have revealed notable alterations in adaptive immune cell populations. However, it rem...

    Authors: Aoife M. O’Byrne, Janne W. Bolt, Chaja M.J. van Ansenwoude, Martijn van der Heijde, Johanna F. Semmelink, Aldo Jongejan, Perry D. Moerland, Mario Maas, Marleen G.H. van de Sande and Lisa G.M. van Baarsen
    Citation: Arthritis Research & Therapy 2025 27:94
  17. Primary Sjögren’s syndrome (pSS) manifests a spectrum of neuropsychological symptoms, primarily cognitive impairment, but the mechanism of central nervous system damage remains unclear. This study sought to an...

    Authors: Chunfeng Hu, Luoyu Wang, Jiao Huang, Yushan Shang, Xiaofang Zhang, Xinyun Du, Huijun Cao, Zhijiang Han and Peiying Wei
    Citation: Arthritis Research & Therapy 2025 27:93
  18. Inflammatory cytokine levels exhibit a circadian rhythm in sera, peaking from late night to early morning in patients with rheumatoid arthritis (RA). This cytokine kinetics is a recognized therapeutic target. ...

    Authors: Teppei Hashimoto, Kazuyuki Tsuboi, Takeo Abe, Takahiro Yoshikawa, Kazuteru Noguchi, Tetsuya Furukawa, Koji Tateishi, Yasuhiro Terashima, Nao Sibanuma, Naoto Azuma, Takashi Yamane, Kiyoshi Matsui and Akira Hashiramoto
    Citation: Arthritis Research & Therapy 2025 27:91
  19. Recently, several studies have reported that nucleus pulposus (NP) cell ferroptosis plays a key role in IDD. However, the characteristics and molecular mechanisms of cell subsets involved remain unclear. We ai...

    Authors: Shipeng Chen, Jiawei Fu, Jiang Long, Chang Liu, Xuezheng Ai, Dan Long, Xue Leng, Yang Zhang, Zhengao Liao, Changqing Li, Yue Zhou, Shiwu Dong, Bo Huang and Chencheng Feng
    Citation: Arthritis Research & Therapy 2025 27:90
  20. To identify pathways linking cytokine abnormalities to mortality via prognostic factors in patients with anti-melanoma differentiation-associated protein 5 antibodies (anti-MDA5 Ab).

    Authors: Aya Shimizu, Kazuhiro Kurasawa, Tomoka Hiyama, Sara Komatsu, Azusa Kikuchi, Yuhi Yoshida, Anna Hasegawa, Tomoyuki Miyao, Ayae Tanaka, Satoko Arai, Reika Maezawa, Masafumi Arima and Kei Ikeda
    Citation: Arthritis Research & Therapy 2025 27:89
  21. Hydroxychloroquine (HCQ) is commonly used to treat Sjögren syndrome (SS). Glucocorticoids, which are commonly applied for managing primary SS (pSS), can disrupt glucose metabolism and increase diabetes mellitu...

    Authors: Wei-Sheng Chen, Hui-Ching Hsu, Tzu-Min Lin, Yu-Sheng Chang, Yi-Chun Lin, Tzu-Tung Kuo, Yu-Chuan Shen, Shu-Chuan Chen, Jin-Hua Chen, Hsiang-Yen Lee and Chi-Ching Chang
    Citation: Arthritis Research & Therapy 2025 27:88
  22. Vertebral compression fractures (VCF) is a common fragility fracture with high mortality worldwide. The management and prevention of VCF start with a proper nutrition. The Mediterranean diet (MD) is rich in ba...

    Authors: Longyu Zhang, Yi Zhao, Jiao Xu, Shi Yin, Qiang Wang, Zhiwei Jia, Jingpei Ren, Cong Zhao and Xiaohong Mu
    Citation: Arthritis Research & Therapy 2025 27:87
  23. The spike protein-specific humoral response observed after SARS-CoV- 2 vaccination is decreased in rheumatoid arthritis (RA) patients treated with rituximab (RTX). However, when analyzed immediately after vacc...

    Authors: Juliette Marin, Penelope Bourgoin, Noemie Saverna, Celia Cartagena, Pierre Lafforgue, Jean-Marc Busnel and Nathalie Balandraud
    Citation: Arthritis Research & Therapy 2025 27:86
  24. The modified Rodnan skin score (mRSS), a measure of systemic sclerosis (SSc) skin thickness, is agnostic to inflammation and vasculopathy. Previously, we demonstrated the potential of neural network-based digi...

    Authors: Ilayda Gunes, Elana J. Bernstein, Shawn E. Cowper, Gauri Panse, Niki Pradhan, Lucy Duran Camacho, Nicolas Page, Elizabeth Bundschuh, Alyssa Williams, Mary Carns, Kathleen Aren, Sarah Fantus, Elizabeth R. Volkmann, Heather Bukiri, Chase Correia, Vijaya B. Kolachalama…
    Citation: Arthritis Research & Therapy 2025 27:85
  25. Upadacitinib (UPA), an oral Janus kinase inhibitor, has shown efficacy with an acceptable safety profile in rheumatoid arthritis (RA) clinical trials.

    Authors: Andrew Östör, Eugen Feist, Prodromos Sidiropoulos, Jérôme Avouac, Martin Rebella, Rajaie Namas, Erin McDearmon-Blondell, Tianming Gao, Ivan Lagunes-Galindo, Sander Strengholt, Devy Zisman and Suzan Attar
    Citation: Arthritis Research & Therapy 2025 27:84
  26. The present cohort study aimed to evaluate the value of CCL23 in diagnosis, disease activity, and prognosis in patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV).

    Authors: Weiwei Hao, Qianqian Liu, Xiaoping Li, Yiran Xu, Wenjuan Guan, Lei Zhang, Fang Dong, Wenjun Cao, Shengyun Liu and Wei Li
    Citation: Arthritis Research & Therapy 2025 27:83
  27. The present non-inferiority study was designed to compare the effect of discontinuing versus continuing methotrexate (MTX) alongside certolizumab pegol (CZP) on maintaining low disease activity (LDA) in rheuma...

    Authors: Shuji Asai, Toshihisa Kojima, Hajime Ishikawa, Nobumasa Miyake, Masanari Kodera, Hisanori Hasegawa, Yasumori Sobue, Yasuhide Kanayama, Hiromi Shimada, Yuji Hirano, Toshihiko Hidaka, Takayoshi Fujibayashi, Takuya Matsumoto, Tomonori Kobayakawa, Hidekata Yasuoka, Takefumi Kato…
    Citation: Arthritis Research & Therapy 2025 27:82
  28. Osteoarthritis (OA) is a multifactorial and highly prevalent disease in elderly adults; however, its pathogenesis, diagnosis, and treatment are unmet needs nowadays. Research efforts have focused on elucidatin...

    Authors: Betzabeth Pereira Herrera, Kaj Emanuel, Pieter J. Emans, Martijn van Griensven and Berta Cillero-Pastor
    Citation: Arthritis Research & Therapy 2025 27:81
  29. Methotrexate (MTX), a standard treatment for rheumatoid arthritis (RA), is known for its potential kidney and liver toxicity. Whether concomitant use of analgesics, possibly affecting the same organs, has an i...

    Authors: Kai Khoroshun, Carsten Bantel, Falk Hoffmann and Kathrin Jobski
    Citation: Arthritis Research & Therapy 2025 27:80
  30. Inflammation and immune mechanisms play a crucial role in connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH), though they remain inadequately understood. This study aimed to identif...

    Authors: Qianwen Wu, Dongyu Li, Huangshu Ye, Zhangdi Zhou, Yixin Zhang, Miaojia Zhang, Xiaoxuan Sun and Qiang Wang
    Citation: Arthritis Research & Therapy 2025 27:79
  31. We aimed to characterize the phenotype of neuromyelitis optica spectrum disorder (NMOSD) in the presence and absence of Sjogren's disease (SjD) and to develop a predictive nomogram to evaluate the risk of coex...

    Authors: Wanqing Wu, Wenbo Yang, Bo Deng, Helian Li, Xiaoni Liu, Hai Yu, Xiang Zhang, Minrui Liang and Xiangjun Chen
    Citation: Arthritis Research & Therapy 2025 27:78
  32. Idiopathic inflammatory myopathies (IIM) are autoimmune disorders characterized by muscle inflammation and autoreactive B cell responses. The Janus kinase (JAK)-signal transducer and activator of transcription...

    Authors: Ana Merino-Vico, Merve Kocyigit, Giulia Frazzei, Lisa Landman, Louis Boon, Ester M. van Leeuwen, Ingrid E. Lundberg, Anneke J. van der Kooi, Joost Raaphorst, Jan Piet van Hamburg and Sander W. Tas
    Citation: Arthritis Research & Therapy 2025 27:76
  33. The risk of developing osteoporosis (OP) is increased in patients with rheumatoid arthritis (RA), which is associated with poorer prognosis and higher mortality. Many patients with RA may experience bone loss ...

    Authors: Yubo Shao, Yazhu Yang, XiaoYu Yang, Zihang Xu, Hong Zhang, Ning Li, Hao Xu, Yongjian Zhao, Yongjun Wang, Qi Shi and Qianqian Liang
    Citation: Arthritis Research & Therapy 2025 27:75
  34. Immune checkpoint inhibitors (ICI), a type of cancer immunotherapy, can cause side effects including inflammatory arthritis (ICI-IA). Previous studies of ICI-IA do not include a thorough characterization of as...

    Authors: Elise F. Gray-Gaillard, Ami A. Shah, Clifton O. Bingham III, Jennifer H. Elisseeff, Joseph Murray, Julie Brahmer, Patrick Forde, Valsamo Anagnostou, Jennifer Mammen and Laura C. Cappelli
    Citation: Arthritis Research & Therapy 2025 27:74
  35. Authors: Betti Giusti, Gabriella Fibbi, Francesca Margheri, Simona Serratì, Luciana Rossi, Filippo Poggi, Ilaria Lapini, Alberto Magi, Angela Del Rosso, Marina Cinelli, Serena Guiducci, Bashar Kahaleh, Laura Bazzichi, Stefano Bombardieri, Marco Matucci-Cerinic, Gian Franco Gensini…
    Citation: Arthritis Research & Therapy 2025 27:73
  36. Kidney involvement is frequent in SLE, with proliferative lupus nephritis (LN) forms and nephritic flares being key predictors of poor outcomes. Conflicting results have been reported for anti-C1q antibodies a...

    Authors: Marta Calatroni, Emanuele Conte, Matteo Stella, Federica De Liso, Francesco Reggiani and Gabriella Moroni
    Citation: Arthritis Research & Therapy 2025 27:72
  37. Patients with systemic juvenile idiopathic arthritis (sJIA) exhibit highly heterogeneous pain manifestations, which significantly impact their quality of life and disease prognosis. An understanding of the pai...

    Authors: Hui Zhang, Xiaoqiong Wei, Wei Liu, Hongyao Leng, Qiao Shen, Xin Wan, Ximing Xu and Xianlan Zheng
    Citation: Arthritis Research & Therapy 2025 27:71
  38. Pain remains a principal complaint for people with psoriatic arthritis (PsA), despite successful mitigation of inflammation. This situation alludes to the co-existence of distinct pain mechanisms. Nociceptive ...

    Authors: Flavia Sunzini, Kristian Stefanov, Salim Al-Wasity, Chelsea Kaplan, Andrew Schrepf, Noah Waller, Steven Harte, Richard Harris, Daniel J. Clauw, John McLean, Stefan Siebert, Carl S. Goodyear, Gordon D. Waiter and Neil Basu
    Citation: Arthritis Research & Therapy 2025 27:70
  39. Osteoarthritis (OA) is associated with abnormal lipid metabolism, wherein elevated levels of phospholipids (PLs) and sphingolipids (SLs) in human and canine synovial fluid (SF) have been observed. The aim of t...

    Authors: Gerrit Eichner, Gerhard Liebisch, Christiane Hild, Markus Rickert and Juergen Steinmeyer
    Citation: Arthritis Research & Therapy 2025 27:69
  40. Facet joint osteoarthritis (OA) is prevalent in patients with adolescent idiopathic scoliosis (AIS). The most pronounced OA presents above and below the curve's apex where the intervertebral rotation is the gr...

    Authors: Kai Sheng, Daniel G. Bisson, Neil Saran, Jake Bourdages, Christopher Coluni, Kirby Upshaw, Kerstin Tiedemann, Svetlana V. Komarova, Jean A. Ouellet and Lisbet Haglund
    Citation: Arthritis Research & Therapy 2025 27:68
  41. Studying pain in rodent models of arthritis is challenging. For example, assessing functional changes in joint neurons is challenging due to their relative scarcity amongst all sensory neurons. Additionally, s...

    Authors: George L. Goodwin, Alina-Cristina Marin, Julia Vlachaki Walker, Carl Hobbs and Franziska Denk
    Citation: Arthritis Research & Therapy 2025 27:67
  42. To evaluate the use of hydroxychloroquine (HCQ) and its impact on the Health Assessment Questionnaire disability index(HAQ-DI) and the Cochin Hand Function Status(CHFS) in a large Systemic Sclerosis (SSc) cohort.

    Authors: S. Bellando-Randone, H. Wilhalme, C. Bruni, L. Czirjak, O. Distler, Y. Allanore, G. Cuomo, C. Denton, F. Del Galdo, A. M. Gheorghiu, V. Riccieri, U. Walker, M. E. Truchetet, M. C. Vonk, I. Foeldvari, M. Matucci-Cerinic…
    Citation: Arthritis Research & Therapy 2025 27:66
  43. Undifferentiated arthritis (UA) often develops into rheumatoid arthritis (RA), but predicting disease progression from seronegative UA remains challenging because seronegative RA often does not meet the classi...

    Authors: Takayuki Fujii, Koichi Murata, Hirohiko Kohjitani, Akira Onishi, Kosaku Murakami, Masao Tanaka, Wataru Yamamoto, Koji Nagai, Ayaka Yoshikawa, Yuki Etani, Yasutaka Okita, Naofumi Yoshida, Hideki Amuro, Tadashi Okano, Yo Ueda, Takaichi Okano…
    Citation: Arthritis Research & Therapy 2025 27:65
  44. Authors: Xiaomei Yang, Qingwei Guo, Tingting Feng, Qiqi Lu, Luna Ge, Jihong Pan, Kehong Bi, Li Qiao, Lei Tian, Tianhua Xie, Chengfang Yao, Guanhua Song and Lin Wang
    Citation: Arthritis Research & Therapy 2025 27:64

    The original article was published in Arthritis Research & Therapy 2020 22:184

  45. We used data from the SENSCIS and SENSCIS-ON trials to assess decline in forced vital capacity (FVC) in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD) who received long-term tr...

    Authors: Oliver Distler, Madelon C Vonk, Arata Azuma, Maureen D. Mayes, Dinesh Khanna, Kristin B. Highland, Gerrit Toenges, Margarida Alves and Yannick Allanore
    Citation: Arthritis Research & Therapy 2025 27:63
  46. This study aimed to characterize nailfold videocapillaroscopy (NVC) features in patients with different subtypes of Idiopathic inflammatory myopathy (IIM) and to investigate the correlations between NVC findin...

    Authors: Mingwei Tang, Jia Shi, Yiyun Pang, Shuang Zhou, Jinjing Liu, Chanyuan Wu, Mengtao Li, Xiaofeng Zeng and Qian Wang
    Citation: Arthritis Research & Therapy 2025 27:62
  47. Juvenile idiopathic arthritis-associated uveitis (JIAU) typically takes a chronic course, frequently leading to ocular complications and often requiring long-term treatment. The present study assesses the 5-ye...

    Authors: Karoline Baquet-Walscheid, Kirsten Minden, Martina Niewerth, Frank Dressler, Ivan Foeldvari, Dirk Foell, Johannes-Peter Haas, Gerd Horneff, Anton Hospach, Tilmann Kallinich, Jasmin Kümmerle-Deschner, Kirsten Mönkemöller, Christoph Tappeiner, Daniel Windschall, Jens Klotsche and Arnd Heiligenhaus
    Citation: Arthritis Research & Therapy 2025 27:61

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 4.4
    5-year Journal Impact Factor: 4.9
    Source Normalized Impact per Paper (SNIP): 1.294
    SCImago Journal Rank (SJR): 1.518

    Speed 2024
    Submission to first editorial decision (median days): 11
    Submission to acceptance (median days): 118

    Usage 2024
    Downloads: 3,978,337
    Altmetric mentions: 1,452