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Table 6 Psychological factors and therapy according to chronification stage

From: Pain chronification and the important role of non-disease-specific symptoms in patients with systemic sclerosis

Pain chronification (MPSS), total of patients, n = 115

Stage I, n = 40 (34.8%)

Stage II, n = 52 (45.2%)

Stage III, n = 23 (20.0%)

HADS Anxiety Score

 Positive

1/37 (2.7%)

7/46 (15.2%)

9/21 (42.9%)

 Borderline

6/37 (16.2%)

9/46 (19.6%)

6/21 (28.6%)

HADS Depression Score

 Positive

1/37 (2.7%)

4/45 (8.9%)

6/21 (28.6%)

 Borderline

3/37 (8.1%)

4/45 (8.9%)

6/21 (28.6%)

MFHW ≤ 10

3/39 (7.7%)

8/48 (16.7%)

9/23 (39.1%)

Analgesic drug therapy overall

12/40 (30.0%)

30/52 (57.7%)

19/23 (82.6%)

 Analgesics WHO I (non-opioids)

12/40 (30.0%)

29/52 (55.8%)

16/23 (69.5%)

 Analgesics WHO II (mild opioids)

1/40 (2.5%)

4/52 (7.6%)

7/23 (30.4%)

 Analgesics WHO III (strong opioids)

0/40 (0.0%)

1/52 (1.9%)

5/23 (21.7%)

Adjuvant pain medication

 Antidepressants

3/40 (7.5%)

9/52 (17.3%)

5/23 (21.7%)

 Anticonvulsants

0/40 (0.0%)

2/52 (3.8%)

1/23 (4.3%)

Ambulant examination or therapy by

 Pain therapist

1/39 (2.6%)

1/50 (2.0%)

3/23 (13.0%)

 Psychiatrist or psychologist

0/39 (0.0%)

3/50 (6.0%)

7/23 (30.4%)

Pain-related stationary treatment

4/34 (11.8%)

13/47 (27.7%)

13/20 (65.0%)

Pain-related stay in rehabilitation facility

2/33 (6.1%)

2/45 (4.4%)

7/19 (36.8%)

  1. Variables are presented as mean ± SD for normal distribution or as median with the 1st and 3rd quartiles (Q1, Q3) for non-normal distribution. Frequencies are shown as x/y: x = number of patients with item present, y = numbers of patients with accessible data; missing values can be calculated n − y
  2. HADS hospital anxiety and depression scale, MFHW Marburger Fragebogen zum habituellen Wohlbefinden (Marburg questionnaire on habitual health findings), MPSS Mainz Pain Staging System, n number, WHO World Health Organization