Fig. 1

SMAD2 level was decreased in RA patients. A, B, E SMAD2 expression in synovial tissues from RA patients and non-RA patients was detected by Western blot and RT-PCR. C, D, F SMAD2 expression in FLS isolated from RA patients (FLS-RA) and non-RA patients (FLS-NC) was detected by Western blot and RT-PCR. G Positive marker (Vimentin) of FLS was detected by immunofluorescence. The experiment was repeated three times and statistical data was presented as mean ± SD. * P<0.05