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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: SMAD2 inhibits pyroptosis of fibroblast-like synoviocytes and secretion of inflammatory factors via the TGF-β pathway in rheumatoid arthritis

Fig. 3

Overexpression of SMAD2 alleviated FLS-RA pyroptosis. A, B Apoptosis rate of FLS-RA was detected by flow cytometry in three groups. C, D The percentage of caspase-1 positive FLS was detected by flow cytometry in three groups. E Electron microscope of three groups of FLS. The green arrow means pseudopodia. The yellow arrow means small pores. The red arrow means microvilli. The experiment was repeated three times and statistical data was presented as mean ± SD. In B, D, * means comparison between control and nigericin groups. # means comparison between nigericin and nigericin+SMAD2 groups. * ,# P<0.05

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Arthritis Research & Therapy

ISSN: 1478-6362

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