Fig. 7

Inhibition of ADAM8 alleviates OA progression in vivo. A Schematic diagram of the in vivo experiments. B-C H&E staining and OARSI score of rat knee joint. D-E Safranin O staining of rat knee joint. F-G Immunohistochemical staining and quantitative analysis for ADAM8 of decalcified bone sections. Scale bars, 200 µm. *P < 0.05; **P < 0.01