Fig. 2

Molecular signatures in the SLE patients in different disease states. A GO enrichment analysis of the DEGs among the three groups. B Heatmap of the differentially expressed immune-related pathways identified from GSVA analysis. The top panel contains the pathways that are down-regulated in active patients and recovered in remission patients. The middle panel contains the pathways that are up-regulated in active patients and down-regulated in remission patients. The bottom panel contains the pathways that are up-regulated in active patients and remained up-regulated in remission patients (AP: Active Patient, RP: Remission Patient, HC: Healthy Control). C Boxplot of the clinical records compared between active patients and remission patients