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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Identification and verification of a novel signature that combines cuproptosis-related genes with ferroptosis-related genes in osteoarthritis using bioinformatics analysis and experimental validation

Fig. 6

Experimental validation of four biomarkers. a Representative immunofluorescence staining images of the four biomarker proteins (p21, FZD7, GABARAPL2, and ZIP14) in the normal and OA groups, with nuclei stained blue with 4’,6-diamidino-2-phenylindole. Scale bar = 25 µm. b Semi-quantitative analysis of mean fluorescence intensity of the four biomarker proteins in the normal and OA groups (n = 6). (c, d) Representative western blotting and statistical comparisons of the four biomarker proteins in the normal and OA groups (n = 6). *p < 0.05, **p < 0.01, all by independent samples t-test

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Arthritis Research & Therapy

ISSN: 1478-6362

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