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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation

Fig. 3

CD11b deficiency exacerbated local and systemic inflammation in MSU-induced gouty arthritis. a) Representative images of H&E-stained histological knee sections from WT and CD11b KO mice injected i.a. with 300 μg of MSU crystals for 6 h. b Histological sections in (a) were scored for cell infiltration using an arbitrary scale from 0 to 3 and expressed as mean±SD of at least 7 mice per group. c IL-1β production in the sera of mice injected with MSU crystals for 6h. Data show mean ± SD of 8-11 mice per group

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Arthritis Research & Therapy

ISSN: 1478-6362

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