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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation

Fig. 4

CD11b deficiency favors glycolysis in macrophages. BMDMs from WT or CD11b-deficient mice were isolated and analyzed for (a) Time course of real-time changes in the ECAR after Glycolysis Stress Assay. b Time-course of real-time changes in the OCR after Cell Mito Stress Assay. c iATP levels. d Expression of genes involved in glycolysis. G6PD2, Aldoa and LDHA were measured by qRT-PCR and expressed as fold increase over WT cells. Data shown represent mean ± SD with group size n=3-4

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Arthritis Research & Therapy

ISSN: 1478-6362

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