Table 2 Changes over 24 months in obesity and imaging markers BMI: body mass index, IPFP CSA: cross sectional area of infrapatellar fat pad, SCATthigh: subcutaneous fat assessment around distal thigh, Δ: changes over 24 months from baseline, Hoffa synovitis and effusion synovitis were scored based on MOAKS

Values at 24 months

BMI (kg/m²)

29.33 ± 5.07

28.20 ± 4.90

0.006

Abdominal circumference (cm)

105.16 ± 13.43

102.11 ± 12.26

0.004

IPFP CSA (cm²)

6.96 ± 1.20

6.23 ± 1.11

< 0.001

SCATthigh (cm²)

6.54 ± 2.05

5.87 ± 1.88

< 0.001

Hoffa synovitis

1.25 ± 0.71

0.32 ± 0.47

< 0.001

Effusion synovitis

1.39 ± 0.74

0.37 ± 0.49

< 0.001

Change over 24 months

Δ BMI (kg/m²)

0.22 ± 1.76

0.14 ± 1.95

0.633

Δ Abdominal circumference (cm)

1.40 ± 9.32

1.33 ± 9.67

0.934

Δ IPFP CSA (cm²)

0.47 ± 0.54

-0.27 ± 0.43

< 0.001

Δ SCATthigh (cm²)

0.84 ± 1.36

0.38 ± 1.19

< 0.001

Δ Hoffa synovitis

0.45 ± 0.84

-0.13 ± 0.5

< 0.001

Δ Effusion synovitis

0.67 ± 0.77

-0.06 ± 0.52

< 0.001