Infrapatellar fat pad size and subcutaneous fat in knee osteoarthritis radiographic progression: data from the osteoarthritis initiative

Table 3 Changes of markers of obesity and synovitis over 24 months (dichotomous analysis)

	All	Case	Control	P
BMI increase greater than 5% [n = 593, n(%)]	103 (17.4)	51 (17.2)	52 (17.5)	1.000
Abdominal circumference increased greater than 5 cm from baseline [n = 587, n(%)]	161 (27.4)	76 (26.0)	85 (28.8)	0.461
ΔSCATthigh greater than 1 SD [n = 563, n(%)]	52 (9.2)	39 (13.9)	13 (4.6)	< 0.001
ΔIPFP CSA greater than 1 SD [n = 566, n(%)]	85 (15.0)	83 (29.4)	2 (0.7)	< 0.001
Hoffa synovitis worsened [n = 566, n(%)]	146 (25.8)	130 (46.1)	16 (5.6)	< 0.001
Effusion synovitis worsened [n = 566, n(%)]	192 (33.9)	162 (57.4)	30 (10.6)	< 0.001

BMI: body mass index, IPFP CSA: cross sectional area of infrapatellar fat pad, SCATthigh: subcutaneous fat assessment around
distal thigh, Δ: changes over 24 months from baseline, Hoffa synovitis and effusion synovitis were scored based on MOAKS

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