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Table 5 Mediation analysis of the effect of obesity indicators change over 2 years on KOA progression mediated by IPFP CSA change over 2 years

From: Infrapatellar fat pad size and subcutaneous fat in knee osteoarthritis radiographic progression: data from the osteoarthritis initiative

Independent variable (X)

Indirect effect coefficient (95% CI)

Direct effect coefficient (95% CI)

Mediation (%)

All (n = 630)

   

Baseline BMI

0.0721 (0.0340, 0.1188)

0.0107 (-0.0343, 0.0557)

87

Men only (n = 184)

   

Baseline BMI

0.0499 (-0.0395, 0.1600)

-0.0105 (-0.1132, 0.923)

 

Women only (n = 446)

   

Baseline BMI

0.0825 (0.0350, 0.1424)

0.0165 (-0.0345, 0.0675)

83.3

  1. KOA: knee osteoarthritis, IPFP CSA: cross sectional area of infrapatellar fat pad, CI: confidence interval, BMI: body mass index