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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: TGFβ signaling pathway is altered by HLA-B27 expression, resulting in pathogenic consequences relevant for spondyloarthritis

Fig. 6

B27 rats Tn cultured under Th17 polarizing conditions produce heightened levels of IL-17. Sorted-naive T cells (CD4+CD25CD62L+) from B27 or control (NTG-circle or B7-triangle) rats were cultured in Th17 differentiation conditions as indicated in figure legend. At day-6, IL-17 levels were evaluated in supernatants by ELISA. Values are mean + SEM of 3 rats/group. Paired t test * p < 0.05 **p < 0.005

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