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Table 2 Odds ratios for elevated serum IgG4 levels in the 1,201 participants

From: Factors related to elevated serum immunoglobulin G4 (IgG4) levels in a Japanese general population

Variable

Unadjusted

Age- and sex-adjusted

OR

(95% CI)

P-value

OR

(95% CI)

P-value

Age (years)

1.032

(1.003 to 1.062)

0.028

1.033

(1.004 to 1.063)

0.027

Male gender

2.666

(1.372 to 5.180)

0.004

2.683

(1.379 to 5.220)

0.004

BMI (kg/m2)

1.011

(0.921 to 1.110)

0.814

  

Systolic BP (mmHg)

0.993

(0.976 to 1.010)

0.399

  

Diastolic BP (mmHg)

0.983

(0.956 to 1.010)

0.223

  

Smoking history

1.742

(0.931 to 3.261)

0.083

  

Allergic disease

1.483

(0.601 to 3.661)

0.393

  

History of Malignancy

0.777

(0.182 to 3.316)

0.734

  

Fraction of Eosinophil (%)

1.067

(0.943 to 1.207)

0.304

  

Serum IgE level

(per100 IU/mL)

1.021

(0.991 to 1.051)

0.171

  

Serum CH50 level (U/mL)

0.999

(0.965 to 1.033)

0.940

  

Serum CRP level (mg/dL)

1.149

(0.732 to 1.803)

0.546

  

ANA

2.332

(0.872 to 6.235)

0.092

  

RF

1.951

(0.733 to 5.193)

0.181

  

eGFR-creatinine (mL/min/1.73m2)

0.999

(0.977 to 1.021)

0.902

  

eGFR-cystatin-C (mL/min/1.73m2)

0.980

(0.964 to 0.997)

0.019

0.986

(0.965 to 1.007)

0.191

LDL-cholesterol (mg/dL)

1.002

(0.988 to 1.016)

0.802

  

HDL-cholesterol (mg/dL)

0.973

(0.953 to 0.994)

0.012

0.982

(0.961 to 1.003)

0.100

Triglyceride (mg/dL)

1.002

(1.000 to 1.005)

0.079

  

Uric acid (mg/dL)

1.189

(0.961 to 1.471)

0.111

  

HbA1c (%)

1.513

(1.107 to 2.068)

0.009

1.370

(0.980 to 1.916)

0.065

Protein intake (%)

0.893

(0.798 to 1.000)

0.049

0.898

(0.801 to 1.007)

0.066

Lipid intake (%)

0.919

(0.869 to 0.972)

0.003

0.937

(0.884 to 0.994)

0.030

Carbohydrate intake (%)

1.044

(1.003 to 1.086)

0.033

1.043

(1.002 to 1.085)

0.040

Polyunsaturated fatty acids intake (%)

0.713

(0.564 to 0.901)

0.005

0.769

(0.606 to 0.978)

0.032

Saturated fatty acids intake (%)

0.818

(0.683 to 0.981)

0.030

0.875

(0.724 to 1.057)

0.166

  1. Abbreviations ANA: anti-nuclear antibody; BMI: body mass index; BP: blood pressure; CRP: C-reactive protein; eGFR: estimated glomerular filtration rate; HbA1c: hemoglobin A1c; HDL: high-density lipoprotein; IgG: immunoglobulin G; IgG4: immunoglobulin G4; IgE: immunoglobulin E; LDL: low-density lipoprotein; RF: rheumatoid factor
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Arthritis Research & Therapy

ISSN: 1478-6362

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