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Table 1 Descriptive characteristics of assessed patients

From: Diminished expression of the ubiquitin-proteasome system in early treatment-naïve patients with rheumatoid arthritis and concomitant type 2 diabetes may be linked to IL-1 pathway hyper-activity; results from PEAC cohort

Clinical Variables

RA patients

RA/T2D patients

P values

Age, mean ± SD, years

54.7 ± 11.7

54.9 ± 11.5

0.952

Male Gender, n (%)

5 (31.5)

5 (31.5)

0.999

BMI, mean ± SD

24.7 ± 5.2

29.2 ± 5.0

0.035

Rheumatoid factor, n (%)

12 (75.0)

8 (50.0)

0.273

ACPA, n (%)

12 (75.0)

10 (62.5)

0.531

DAS28-CRP, mean ± SD

5.6 ± 0.9

5.4 ± 1.2

0.695

DAS28-ESR, mean ± SD

6.0 ± 1.5

5.9 ± 1.5

0.785

Tender joints, mean ± SD

14.1 ± 6.7

13.3 ± 6.7

0.766

Swollen joints, mean ± SD

7.8 ± 4.6

9.0 ± 4.8

0.485

VAS global health, mean ± SD

67.1 ± 28.1

56.1 ± 25.9

0.263

ESR, mm/h, mean ± SD

42.7 ± 33.8

44.2 ± 38.2

0.908

CRP, mg/L, mean ± SD

15.0 ± 13.1

15.8 ± 18.3

0.892

  1. Abbreviations: RA Rheumatoid arthritis, T2D Type 2 diabetes, BMI Body mass index, ACPA Anti-citrullinated protein antibodies, DAS28 Disease activity score in 28 joints, CRP C reactive protein, ESR Erythrocyte sedimentation rate, VAS Visual analogue scale