Table 2 The frequency of each B cell subset in active (n = 21), inactive SLE (n = 11), and HCs (n = 16)
Parameters | Active SLE Median [IQR] | Inactive SLE Median [IQR] | Healthy controls Median [IQR] | p-value |
|---|---|---|---|---|
NAV B cell | 61.00 [56.55–69.85] | 60.40 [56.70–66] | 53.10 [50.3–56.1] | < 0.0001 |
DN B cell | 26.90 [23.30-30.38] | 21.00 [18.91–22.72] | 12.90 [11.20-16.77] | < 0.0001 |
SWM B cell | 16.20 [13.45–32.48] | 20.30 [16.04–28.70] | 11.20 [5.66–20.30] | ns |
USW B cell | 3.21 [2.16–5.01] | 2.11 [1.71–4.03] | 4.71 [3.02–5.15] | ns |
DN2 B cell | 25.11 [19.85–27.71] | 20.00 [18.16–22.30] | 8.55 [8.11–9.44] | < 0.001 |
rNAV B cell | 36.37 [32.85–41.55] | 36.09 [21.72–40.21] | 42.55 [41.40–50.5] | < 0.0001 |
aNAV B cell | 16.88 [14.22–19.07] | 14.02 [11.92–15.78] | 3.58 [2.99–5.12] | < 0.001 |