Fig. 1
From: Oxysterols contribute to immune cell recruitment in SLE skin lesions
Oxysterols were increased in SLE skin lesions. (A) Process flowchart for targeted lipidomics analysis (n = 3). (B) Paired t-test line graph showing the significant difference in sterol levels between the lesional skin and non-lesional skin of MRL/Lpr mice (p = 0.0234) (n = 3). (C) Paired t-test line graphs displaying the significant differences in oxysterols levels between the lesional skin and non-lesional skin of MRL/Lpr. The graphs include desmosterol/zymosterol (p = 0.0288), dehydrocholesterol (p = 0.0064), 4β-hydroxycholesterol (p = 0.0227), 6α-hydroxy-5α-cholestanol (p = 0.0278), 5α,6α-epoxycholesterol (p = 0.0156), 5α,6β-epoxycholesterol (p = 0.0202), 5α-cholest-8(14)-ene-3β,15α-diol (p = 0.0166) and 7-ketocholesterol (p = 0.0066) (n = 3). The p values were calculated using paired t test. LC/MS: liquid chromatography-mass spectrometry