Fig. 4
From: Investigation of GPM6B as a novel therapeutic target in Osteoarthritis
GPM6B-regulated MMPs in FLS. (A) qPCR analysis of MMP levels in primary FLS without IL-1β stimulation. (B) qPCR analysis of MMP levels in primary FLS isolated from synovial tissues of patients with OA and IL-1β stimulation. (C) Western blot analysis of MMP levels in primary FLS with IL-1β stimulation. (D) EdU incorporation assay was used to evaluate FLS proliferation with IL-1β stimulation, and the cells were treated as indicated. n = 3 per group; scale bars: 75 μm. Data are presented as the mean ± standard error, * P < 0.05, ** P < 0.01 versus NC