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Table 3 Multivariate regression analysis for D2T*

From: Timely escalation to second-line therapies after failure of methotrexate in patients with early rheumatoid arthritis does not reduce the risk of becoming difficult-to-treat

 

OR

95% CI

p

female gender

5.11

1.20 to 21.86

0.03

disease duration

0.98

0.96 to 0.99

0.04

number of swollen joints

1.26

1.05 to 1.51

0.01

VAS pain

1.02

1.01 to 1.03

0.04

RF and ACPA negative

2.58

1.09 to 6.91

0.03

  1. D2T = Difficult-to-Treat; VAS = visual analogue scale; RF = rheumatoid factor; ACPA = anti-citrullinated peptide antibodies
  2. *D2T according to the EULAR definition [5].