From: Timely escalation to second-line therapies after failure of methotrexate in patients with early rheumatoid arthritis does not reduce the risk of becoming difficult-to-treat
OR
95% CI
p
female gender
5.11
1.20 to 21.86
0.03
disease duration
0.98
0.96 to 0.99
0.04
number of swollen joints
1.26
1.05 to 1.51
0.01
VAS pain
1.02
1.01 to 1.03
RF and ACPA negative
2.58
1.09 to 6.91