Table 2 Comorbidities and extra-articular manifestations of the disease according to the D2T criteria
|  | D2T-RA (n = 71) | Non D2T-RA (n = 387) | P-value |
|---|---|---|---|
Hypertension [n (%)] | 28 (39.44%) | 133 (34.37%) | 0.411 |
Dyslipidemia [n (%)] | 26 (36.62%) | 118 (30.89%) | 0.342 |
Major Cardiovascular Events [n (%)] | 10 (14.08%) | 30 (7.75%) | 0.087 |
Obesity [n (%)] | 17 (33.33%) | 58 (19.21%) | 0.021 |
Diabetes [n (%)] | 9 (12.68%) | 33 (8.53%) | 0.269 |
Diverticular Disease [n (%)] | 7 (9.86%) | 21 (5.43%) | 0.158 |
Sjogren Disease [n (%)] | 4 (5.63%) | 10 (2.58%) | 0.181 |
Thyroid disease [n (%)] | 17 (33.33%) | 98 (23.94%) | 0.805 |
GERD [n (%)] | 13 (18.31%) | 47 (12.14%) | 0.160 |
Thrombotic Events [n (%)] | 6 (8.45%) | 21 (5.43%) | 0.324 |
Malignancies [n (%)] | 23 (32.39%) | 126 (32.56%) | 0.978 |
Asthma/COPD [n (%)] | 10 (14.08%) | 54 (13.95%) | 0.977 |
Anxious or Depressive Syndrome [n (%)] | 9 (12.68%) | 35 (9.04%) | 0.342 |
Osteoporosis | 25 (53.19%) | 140 (59.07%) | 0.456 |
Fibromyalgia [n (%)] | 18 (25.35%) | 37 (9.56%) |  < 0.0001 |
ILD [n (%)] | 13 (23.21%) | 64 (23.27%) | 0.992 |
Rheumatoid Nodules [n (%)] | 5 (7.04%) | 12 (3.10%) | 0.116 |