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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Gout-associated SNP at the IL1RN-IL1F10 region is associated with altered cytokine production in PBMCs of patients with gout and controls

Fig. 1

Locus Zoom plots of IL1RN locus in Euroean Gout GWAS, GTEx and eQTLGen dataset (whole blood). The IL1RN rs9973741 SNP is labeled in purple. Each dot represents an individual SNP with the colour representing the LD with the most associated (lead) SNP with gout in the panel. The vertical axis represents -log10 (p value) for assessment of the association of the SNP with IL1RN expression. The genes within the region are annotated, and the direction of the transcripts is shown by arrows. The plot was generated using LocusZoom [23]. Values for posterior probability of colocalisation (PPC) are included in the panels

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Arthritis Research & Therapy

ISSN: 1478-6362

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