Table 1 Comparison between patients treated with a daily colchicine dose of 2.5 mg and others
Variable | Daily colchicine dose < 2.5 | Daily colchicine dose = 2.5 | p-Value |
|---|---|---|---|
N = 242 | N = 30 | ||
Sex | 0.018 | ||
M | 116 (47.93%) | 7 (23.33%) | |
W | 126 (52.07%) | 23 (76.67%) | |
N = 242% | N = 30 | ||
M694V/M694V pathogenic variant | 198 (81.82%) N = 242 | 27 (90.00%) N = 30 | 0.735 |
Age, years | 41.96 (± 16.75) | 36.57 (± 12.84) | 0.139 |
Range: (17.0; 84.0) | Range: (19.0; 67.0) | ||
N = 242 | N = 30 | ||
BMI, kg/m2 | 24.34 (± 4.67) | 22.83 (± 4.12) | 0.076 |
Range: (15.2; 44.9) | Range: (16.4; 31.4) | ||
N = 234 | N = 29 | ||
Age at diagnosis, years | 13.92 (± 12.46) | 10.67 (± 10.56) | 0.084 |
Range: (1.0; 56.0) | Range: (1.0; 40.0) | ||
N = 230 | N = 29 | ||
Biotherapy | 0.804 | ||
Yes | 44 (18.18%) | 6 (20.0%) | |
No | 198 (81.82%) | 24 (80.0%) | |
N = 242 | N = 30 | ||
Weight, kg | 68.52 (± 14.92) | 61.74 (± 12.27) | 0.019 |
Range: (37.0; 109.0) | Range: (41.0; 89.0) | ||
N = 238 | N = 29 | ||
Creatinine, µmol/L | 73.06 (± 52.82) | 54.21 (± 11.28) | <0.001 |
Range: (35.0; 721.0) | Range: (34.0; 82.0) | ||
N = 227 | N = 28 | ||
Amyloidosis | 0.614 | ||
Yes | 11 (4.72%) | 0 (0.0%) | |
No | 222 (95.28%) | 28 (100.0%) | |
N = 233 | N = 28 |