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Table 1 Comparison of demographic and clinical characteristics between r-axSpA with and without fatty lesions

From: The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions

 

Fatty lesions (n = 48)

No fatty lesions (n = 25)

p value

Male (%)

40 (83.3%)

17 (68.0%)

0.133

Age (year)

34.2 ± 7.5

33.2 ± 8.6

0.598

BMI (kg/m2)a

23.2 (20.5–25.5)

23.9 (21.3–26.5)

0.450

Duration (year)a

5.3 (3.0-11.5)

8.0 (2.3–10.0)

0.701

Smoking status (%)

10 (20.8%)

7 (28.0%)

0.492

HLA-B27 positive (%)

45 (93.8%)

23 (92.0%)

1.000

ESR (mm/H)a

17.0 (9.0-27.8)

13.0 (6.0-28.5)

0.436

CRP (mg/L)a

4.7 (1.9–13.3)

5.3 (0.8–11.6)

0.613

ASDAS-ESRa

2.0 (1.2–2.9)

1.6 (1.0–3.0)

0.429

ASDAS-CRPa

1.8 (1.1–2.9)

1.6 (0.9–2.8)

0.475

BASDAIa

1.8 (0.8–3.2)

0.9 (0.4–3.1)

0.317

bDMARDs rate

42 (87.5%)

21 (84.0%)

0.727

mSASSSa*

4 (2–9)

1 (0–3)

< 0.001

Sclerostin (pg/ml)*

254.2 (204.8-341.3)

462.1 (360.4-631.7)

< 0.001

OPG (pg/ml)

412.4 ± 289.1

370.2 ± 271.6

0.548

PINP (pg/ml)

2639.5 ± 1298.7

2979.5 ± 1306.7

0.293

CTX-I (ng/ml)a

0.42 (0.27–0.68)

0.34 (0.21–0.54)

0.313

OC (ng/ml)a

57.6 (35.7–95.1)

54.5 (26.6-112.6)

0.857

  1. r-axSpA = radiographic axial spondyloarthritis; BMI = body mass index; HLA-B27 = human leukocyte antigen B27; ESR = erythrocyte sedimentation rate; CRP = C-reactive protein; ASDAS = Axial Spondyloarthritis Disease Activity Score; BASDAI = Bath Ankylosing Spondylitis Disease Activity Index; bDMARDs = biological disease-modifying anti-rheumatic drugs; mSASSS = Modified Stoke Ankylosing Spondylitis Spine Score; OPG = Osteoprotegerin; PINP = Procollagen I N-Terminal Propeptide; CTX-I = Cross Linked C-telopeptide of Type I Collagen; OC = Osteocalcin
  2. aMedian (Interquartile range)
  3. Statistical significance