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Table 2 Univariate and multivariate analysis between CBM scores and clinical variables and biomarkers in r-axSpA with fatty lesions

From: The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions

 

Univariate analysis

Multivariate analysis

Variables

ρ

p value

B (95%CI)

β

p value

Age (year)

0.133

0.366

   

BMI (kg/m2)

0.311

0.031*

0.015 (-0.121, 0.151)

0.019

0.825

Duration (year)

0.025

0.864

   

ESR (mm/H)

0.058

0.694

   

CRP (mg/L)

0.182

0.216

   

ASDAS-ESR

0.022

0.883

   

ASDAS-CRP

0.104

0.483

   

BASDAI

0.041

0.784

   

mSASSS

0.306

0.034*

-0.021 (-0.076, 0.034)

-0.066

0.448

Sclerostin (pg/ml)

-0.920

< 0.001*

-0.040 (-0.049, -0.032)

-0.840

< 0.001*

OPG (pg/ml)

-0.081

0.582

   

PINP (pg/ml)

0.079

0.595

   

CTX-I (ng/ml)

-0.054

0.715

   

OC (ng/ml)

0.022

0.880

   
   

Adjusted R2 = 0.669

  1. r-axSpA = radiographic axial spondyloarthritis; ρ = Spearman’s correlation coefficient; B = Unstandardized coefficient; β = Standardized coefficient; CI = confidence interval ; CBM = the comprehensive Berlin scoring method; BMI = body mass index; ESR = erythrocyte sedimentation rate; CRP = C-reactive protein; ASDAS = Axial Spondyloarthritis Disease Activity Score; BASDAI = Bath Ankylosing Spondylitis Disease Activity Index; SIJ = Sacroiliac joint; mSASSS = Modified Stoke Ankylosing Spondylitis Spine Score; OPG = Osteoprotegerin; PINP = Procollagen I N-Terminal Propeptide; CTX-I = Cross Linked C-telopeptide of Type I Collagen; OC = Osteocalcin; R2 = coefficient of determination
  2. *Statistical significance
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Arthritis Research & Therapy

ISSN: 1478-6362

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