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Table 3 Multiple linear regression analysis models showing independent variables associated with sclerostin levels in r-axSpA patients

From: The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions

 

Dependent variable

Independent variable

Adjusted R2

B (95%CI)

β

p value

Model 1

0.055

 

BMI

 

 Age (year)

 

0.209 (-0.004, 0.422)

0.289

0.054

 ASDAS-CRP

 

1.013 (-0.472, 2.498)

0.198

0.176

 CBM scores

 

0.069 (-0.298, 0.436)

0.055

0.705

Model 2

0.005

 

mSASSS

 

 Age (year)

 

0.438 (-0.111, 0.987)

0.241

0.115

 ASDAS-CRP

 

0.528 (-3.299, 4.355)

0.041

0.782

 CBM scores

 

0.227 (-0.718, 1.173)

0.072

0.630

Model 3

0.689

 

Sclerostin

 

 Age (year)

 

0.127 (-1.963, 2.218)

0.011

0.903

 ASDAS-CRP

 

-4.519 (-19.082, 10.043)

-0.053

0.535

 CBM scores

 

-17.227 (-20.825, -13.628)

-0.827

< 0.001*

  1. r-axSpA = radiographic axial spondyloarthritis; R2 = coefficient of determination; B = Unstandardized coefficient; β = Standardized coefficient; CI = confidence interval ; BMI = body mass index; ASDAS = Axial Spondyloarthritis Disease Activity Score; ESR = erythrocyte sedimentation rate; BASDAI = Bath Ankylosing Spondylitis Disease Activity Index; CBM = the comprehensive Berlin scoring method; mSASSS = Modified Stoke Ankylosing Spondylitis Spine Score; CRP = C-reactive protein;
  2. *Statistical significance