Fig. 2

Overall SHAP value plot after (a) 12 months and (b) 6 months. Figure shows the most important variables in the ACTION/ASCORE combined dataset that were predictive of abatacept retention. Colors indicate the value of the variable: red represents higher numerical values of the variable and blue represents lower numerical values. The bulges in the plot indicate more patients with that value; each dot represents a single patient. Higher SHAP values indicate a higher likelihood of retention. *Evaluable for secondary analysis of clinical efficacy. ACPA anti-citrullinated protein antibody, ACR American College of Rheumatology, BMI body mass index, CDAI Clinical Disease Activity Index, CRP C-reactive protein, DAS28, Disease Activity Score in 28 joints, ESR erythrocyte sedimentation rate, HAQ-DI Health Assessment Questionnaire-disability index, MTX methotrexate, RA rheumatoid arthritis, RF rheumatoid factor, SDAI Simplified Disease Activity Index, SHAP SHapley Additive exPlanation, SJC28 swollen joint count in 28 joints, TJC28 tender joint count in 28 joints, TNFi tumor necrosis factor inhibitor