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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Performance of the modified 2022 ACR/EULAR giant cell arteritis classification criteria without age restriction for discriminating from Takayasu arteritis

Fig. 1

The discriminating ability for GCA and TAK of a combination of clinical parameters was evaluated by C-statistic. Gray highlighting indicates that the item is included in the model 1–7 (A). ESR of ≥ 50 mm/hr or CRP of ≥ 1.0 mg/dL was included in all models. Age at onset ≥ 50 years1, positive temporal artery biopsy2, cranial signs and symptoms (new headache, scalp tenderness, abnormal examination of the temporal artery, sudden visual abnormalities, and jaw claudication)3, PMR, descending thoracic-abdominal aorta involvement4, bilateral axillary artery involvement5, bilateral subclavian and/or axillary artery involvement6 were selected as clinical parameters. The ROC curve was drawn to calculate the area under the ROC curve as a C-statistic. The C statistic represents the ability to discriminate GCA from TAK in model 1 (B), model 2 (C), model 3 (D), model 4 (E), model 5 (F), model 6 (G), and model 7 (H). A value for the C-statistic greater than 0.7 indicates a reasonable and good ability to discriminate between patients with GCA and TAK. CI, confidence interval; ROC, receiver operating characteristic; TAK, Takayasu arteritis

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