Table 2 Comparison of clinical parameters included in the modified 2022 ACR/EULAR GCA classification criteria in patients with GCA and TAK

Age at onset

73.8 (7.7)

35.4 (18.1)

 < 0.001

Age at onset ≥ 50 years, %

100

23.3

 < 0.001

Female, %

66.9

83.7

0.001

New headache, %

61.2

15.9 (18/113)

 < 0.001

Scalp tenderness, %

19.4

0 (0/105)

 < 0.001

Abnormal examination of the temporal artery, %

59.0

0.9 (1/110)

 < 0.001

Sudden visual loss, %

23.7

7.1 (8/113)

 < 0.001

Jaw claudication, %

36.0

5.5 (6/110)

 < 0.001

PMR, %

41.7

0.8 (1/127)

 < 0.001

Myalgia/arthralgia/arthritis, %

56.8

20.5 (25/122)

 < 0.001

Definitive vasculitis on temporal artery biopsy

50.4

0

-

Stenosis of temporal artery by imaging

26.6

0

-

ESR ≥ 50 mm/hr or CRP ≥ 1.0 mg/dL, %

95.7

83.7

0.001

Large-vessel involvement, %

52.5

100

-

Left axially artery, %

10.8

12.4

0.680

Right axially artery, %

8.6

7.0

0.614

Bilateral axillary artery, %

7.2

6.2

0.746

Left subclavian artery, %

29.5

64.3

 < 0.001

Right subclavian artery, %

23.7

36.4

0.023

Bilateral subclavian and/or axillary artery^a, %

21.6

30.2

0.106

Left or right subclavian and/or axillary artery, %

31.7

70.5

 < 0.001

Descending thoracic aorta-abdominal aorta^b, %

23.7

32.6

0.108

Ascending aorta

16.5

48.8

 < 0.001

Aortic arch

25.2

57.4

 < 0.001

Aortic involvement of ≥ two lesions

27.3

58.9

 < 0.001