Performance of the modified 2022 ACR/EULAR giant cell arteritis classification criteria without age restriction for discriminating from Takayasu arteritis

Table 3 Comparison of clinical parameters included in the modified 2022 ACR/EULAR GCA classification criteria in patients with LV-GCA and late-onset (≥ 50 years) TAK

	LV-GCA (n = 73)	Late-onset TAK (n = 30)	P-value
Age, mean (S.D.)	71.1 (7.1)	64.2 (9.0)	0.001
Female, %	72.6	86.7	0.125
New headache, %	39.7	11.5 (3/26)	0.008
Scalp tenderness, %	15.1	0 (0/24)	0.052
Abnormal examination of the temporal artery, %	41.1	0.0 (0/24)	< 0.001
Sudden visual loss, %	12.3	8.0 (2/25)	< 0.001
Jaw claudication, %	23.3	12.0 (3/25)	0.227
PMR, %	27.4	0.0 (0/28)	< 0.001
Myalgia/arthralgia/arthritis, %	49.3	32.1 (9/28)	0.120
CRP, mg/dL, mean (S.D.)	7.1 (5.1)	8.1 (7.2)	0.513
Left axially artery, %	20.5	13.3	0.391
Right axially artery, %	16.4	13.3	0.474
Bilateral axillary artery, %	13.7	10.0	0.440
Left subclavian artery, %	56.2	70.0	0.192
Right subclavian artery, %	45.2	53.3	0.453
Bilateral subclavian and/or axillary artery^a, %	41.1	20.0	0.041
Left or right subclavian and/or axillary artery, %	60.3	76.7	0.113
Descending thoracic aorta-abdominal aorta^b, %	45.2	40.0	0.628
Ascending aorta	31.5	53.3	0.038
Aortic arch	47.9	63.3	0.155
Aortic involvement of ≥ two lesions	52.1	66.7	0.174

Imaging examinations of large-vessel lesions were performed in 135 of the 139 patients at diagnosis of GCA, and 73 had large-vessel lesions as diagnosis of LV-GCA. Categorical variables were examined by using the chi-squared test and Fisher’s exact test. Continuous variables were evaluated by using the Student’s t-test
ACR American College of Rheumatology, CRP C-reactive protein, ESR erythrocyte sedimentation rate, EULAR European Alliance of Associations for Rheumatology, GCA giant cell arteritis, PMR polymyalgia rheumatic, TAK Takayasu arteritis
^aThe presence of lesions of the subclavian and/or axillary arteries on both the left and right sides. The case in which one artery was the subclavian artery and the other was the axillary artery was also included
^bThe involvement of both the descending thoracic aorta and the abdominal aorta

ISSN: 1478-6362