Performance of the modified 2022 ACR/EULAR giant cell arteritis classification criteria without age restriction for discriminating from Takayasu arteritis

Table 5 Clinical features of patients who failed to meet the modified 2022 ACR/EULAR classification criteria of GCA

	GCA (score ≥ 6) (n = 114)	GCA (score ≤ 5) (n = 25)	TAK (n = 129)
Age	74.6 (7.2)	70.2 (8.9)	35.4 (18.1)^**
Age at onset ≥ 50 years, %	100	100	23.3^*
Female, %	64.0	80.0	83.7^**
New headache, %	71.1^*	16.0	15.9
Scalp tenderness, %	23.7^*	0	0
Abnormal examination of the temporal artery, %	71.1^*	4.0	0.9
Sudden visual loss, %	28.1^*	4.0	7.1
Blindness	5.3^*	0	0
Jaw claudication, %	43.9^*	0	5.5
PMR, %	48.2^*	12.0^*	0.8^*
Myalgia/Arthralgia/Arthritis, %	60.5^***	40.0	20.5
CRP	8.12 (5.76)	6.42 (5.74)	6.13 (5.45)
ESR	92.6 (33.3)	73.1 (36.8)	74.0 (36.8)
ESR ≥ 50 mm/hr or CRP ≥ 1.0 mg/dL, %	97.4^***	87.5	83.7
Large-vessel involvement	43.9^*	92.0^*	100^*
Left axially artery, %	10.5	12.0	12.4
Right axially artery, %	9.6	4.0	7.0
Bilateral axillary artery, %	8.8	0	6.2
Left subclavian artery, %	21.1^*	68.0	64.3
Right subclavian artery, %	17.5^*	52.0	36.4
Bilateral subclavian and/or axillary artery^a, %	14.9^*	52.0	30.2
Left or right subclavian and/or axillary artery, %	23.7^*	68.0	70.5
Descending thoracic aorta-abdominal aorta^b, %	21.7	33.3	32.6
Ascending aorta	12.3^*	36.0	48.8
Aortic arch	19.3^*	52.0	57.4

Continuous variables are determined by one-way ANOVA and Turky’s multiple test. Categorical variables are determined by multiple tests using the Z-test
LV-GCA large-vessel giant cell arteritis, OR odds ratios, TAK Takayasu arteritis
^*p < 0.05 compared to the other two groups
^**p < 0.05 comparing TAK to GCA with a score of 6 or higher
^***p < 0.05 comparing GCA with a score of 6 or higher to TAK
^aThe presence of lesions of the subclavian and/or axillary arteries on both the left and right sides. The case in which one artery was the subclavian artery and the other was the axillary artery was also included
^bThe involvement of both the descending thoracic aorta and the abdominal aorta

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