Fig. 6

Rate of resolution of tender joints (HR and 95% CI) after start of tumour necrosis factor inhibitor treatment estimated using overall interval-censored mixed-effects Cox proportional hazards models adjusted for age and sex for different comparisons: A joints along the proximal–distal axis of the upper limb, B finger joints along the anterior–posterior axis of the hand (digits 1–5), C knee compared to elbow. The reference joint(s) are indicated in each panel. The number of swollen joints and the number of patients is shown for each joint location. MCP3 = metacarpophalangeal joint of digit 3; PIP3 = proximal interphalangeal joint of digit 3