Proteomic profiling of human plasma and intervertebral disc tissue reveals matrisomal, but not plasma, biomarkers of disc degeneration

Table 1 Sample demographics. Age, sex, level of operated intervertebral disc, and histological grade of degeneration in samples obtained from donors undergoing discectomy surgery for treatment of low back pain

Sample	Age (Years)	Sex	Operated Disc Level	Histology Grade	Severity
1	35	Female	L5/S1	4	Mild
2	44	Female	L5/S1	5	Mild
3	46	Female	L5/S1	6	Mild
4	55	Female	L5/S1	6	Mild
5	48	Male	L4/5	6	Mild
6	35	Female	L4/5	6	Mild
7	41	Female	L4/5	6	Mild
8	61	Male	L4/5	6	Mild
9	46	Male	L4/5	6	Mild
10	39	Male	L4/5	7	Mild
11	41	Female	L4/5	7	Mild
12	45	Male	L5/S1	7	Mild
13	29	Male	L5/S1	7	Mild
14	31	Male	L4/5	7	Mild
15	36	Female	L4/5	7	Mild
16	84	Female	L5/S1	7	Mild
17	35	Female	L4/5	7	Mild
18	30	Male	L5/S1	7	Mild
19	41	Female	L4/5	10	Severe
20	35	Male	L5/S1	10	Severe
21	40	Female	L5/S1	10	Severe
22	44	Female	L4/5	10	Severe
23	39	Male	L5/S1	10	Severe
24	51	Female	L5/S1	10	Severe
25	35	Male	L5/S1	10	Severe
26	31	Male	L4/5	10	Severe
27	42	Male	L4/5	10	Severe
28	42	Male	L5/S1	10	Severe
29	39	Male	L4/5	11	Severe
30	28	Male	L5/S1	11	Severe
31	49	Male	L5/S1	11	Severe
32	42	Male	L4/5	11	Severe
33	35	Female	L4/5	11	Severe
34	38	Female	L4/5	11	Severe
35	35	Female	L5/S1	11	Severe

ISSN: 1478-6362