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Table 3 Association of asthma with risk of osteoarthritis stratified by potential risk factors via model 2#

From: Asthma, social isolation and loneliness, and risk of incident osteoarthritis

Subgroup

Non-asthma

Asthma

HR (95% CI)

P-interaction

Age (years)

  

0.082

 < 60

1.00 (reference)

1.33 (1.28–1.37)

 

 ≥ 60

1.00 (reference)

1.29 (1.25–1.33)

 

Sex

  

< 0.001

 Women

1.00 (reference)

1.38 (1.34–1.42)

 

 Men

1.00 (reference)

1.24 (1.19–1.29)

 

Ethnic background

  

0.176

 Non-white

1.00 (reference)

1.39 (1.28–1.52)

 

 White

1.00 (reference)

1.32 (1.29–1.35)

 

Townsend deprivation index

  

< 0.001

 < Median

1.00 (reference)

1.27 (1.22–1.31)

 

 ≥Median

1.00 (reference)

1.38 (1.33–1.42)

 

Education (years)

  

0.477

 < 10

1.00 (reference)

1.35 (1.28–1.42)

 

 ≥ 10

1.00 (reference)

1.31 (1.27–1.35)

 

Body mass index (kg/m2)

  

0.530

 < 25

1.00 (reference)

1.36 (1.29–1.43)

 

 25-<30

1.00 (reference)

1.31 (1.26–1.36)

 

 ≥ 30

1.00 (reference)

1.31 (1.26–1.36)

 

Smoking status

  

0.065

 Never

1.00 (reference)

1.31 (1.26–1.35)

 

 Previous

1.00 (reference)

1.32 (1.27–1.37)

 

 Current

1.00 (reference)

1.42 (1.32–1.53)

 

Healthy diet score

 

0.247

 < 3

1.00 (reference)

1.35 (1.29–1.41)

 

 ≥ 3

1.00 (reference)

1.31 (1.27–1.34)

 
  1. #Model 2: adjusted for age, sex, ethnic background, Townsend deprivation index, education years, body mass index, smoking status, alcohol intake and healthy diet score