Table 3 Pregnancy outcomes and disease flares in SLE patients divided by whether fulfilling the conditions for pregnancy
|  | All (n = 347) | Group A: Fulfilling the conditions (n = 180) | Group B: Not fulfilling the conditions (n = 167) | P value |
|---|---|---|---|---|
Live birth, n (%) | 278 (80.1) | 155 (86.1) | 123 (73.7) | 0.004* |
 Gestational week at delivery, median (IQR) | 38.1 (37.1–38.9) | 38.4 (37.7–39.0) | 37.6 (36.4–38.6) | < 0.001* |
 Birthweight (gram), mean (SD) | 2891.3 (497.5) (n = 150) | 2956.7 (397.8) (n = 83) | 2810.2 (591.7) (n = 67) | 0.004* |
 Cesarean section, n (%) | 178 (68.7) | 97 (65.5) | 81 (73.0) | 0.254 |
Adverse pregnancy outcomes, n (%) | 140 (40.3) | 53 (29.4) | 87 (52.1) | < 0.001* |
 Neonatal death | 1 (0.3) | 1 (0.6) | 0 (0.0) | 1.000 |
 Miscarriage | 17 (4.9) | 7 (3.9) | 10 (6.0) | 0.365 |
 Intrauterine fetal demise | 23 (6.6) | 9 (5.0) | 14 (8.4) | 0.206 |
 Therapeutic abortion | 29 (8.4) | 9 (5.0) | 20 (12.0) | 0.019* |
 Preterm delivery | 63 (22.7) | 22 (14.2) | 41 (33.3) | < 0.001* |
 Gestational hypertension | 17 (4.9) | 6 (3.3) | 11 (6.6) | 0.161 |
  Preeclampsia | 11 (3.2) | 2 (1.1) | 9 (5.4) | 0.023* |
Flares during pregnancy and one year postpartum | 121 (38.5) (n = 314) | 56 (32.4) (n = 173) | 65 (46.1) (n = 141) | 0.013* |
 Mild or moderate | 56 (17.8) | 28 (16.2) | 28 (19.9) | 0.398 |
 Severe | 65 (20.7) | 28 (16.2) | 37 (26.2) | 0.029* |
Flares during pregnancy | 58 (20.4) (n = 284) | 23 (14.7) (n = 156) | 35 (27.3) (n = 128) | 0.009* |
 Mild or moderate | 30 (10.6) | 14 (9.0) | 16 (12.5) | 0.336 |
 Severe | 28 (9.9) | 9 (5.8) | 19 (14.8) | 0.011* |
Flares during one year postpartum | 89 (30.1) (n = 296) | 41 (25.2) (n = 163) | 48 (36.1) (n = 133) | 0.041* |
 Mild or moderate | 44 (14.9) | 20 (12.3) | 24 (18.0) | 0.165 |
 Severe | 45 (15.2) | 21 (12.9) | 24 (18.0) | 0.219 |