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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Blood molecular subtypes to guide precision treatment strategies in systemic juvenile idiopathic arthritis

Fig. 1

Molecular signatures of sJIA. (A) Enrichment of JIA-associated signaling pathways and biological processes by GSEA across the JIA subtypes. Normalized enrichment score (NES) indicates the relative degree of overrepresentation across the gene sets. (B) DEG-driven enrichment analysis of sJIA. Upper and lower panels are Gene Ontology (GO) – Biological Processes (BP) and Reactome terms, respectively. (C) GSEA plot of the neutrophil degranulation in sJIA. GSEA = gene-set enrichment analysis, sJIA = systemic juvenile idiopathic arthritis, paJIA = polyarticular juvenile idiopathic arthritis, oaJIA = oligoarticular juvenile idiopathic arthritis, ERA = enthesitis-related arthritis

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Arthritis Research & Therapy

ISSN: 1478-6362

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