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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Establishment of an ex vivo cartilage damage model by combined collagenase treatment and mechanical loading

Fig. 4

Cartilage treated with collagenase II could resist 10–20% compression of cartilage thickness and 25 degrees shear. (A) LDH/EthD staining, SO-FG, IHC-stained with anti-COL2A1, anti-ACAN, and anti-neo-epitopes of aggrecan (n = 3). (B) Quantification of cell viability, COL2A1, ACAN, neo epitope of aggrecan under loading conditions (10–20% compression and 25 degrees shear) on day 3 and day 7. Triangles, dots or square of different color represent individual donors (n = 3). Scale bar = 100 μm

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Arthritis Research & Therapy

ISSN: 1478-6362

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