Fig. 1

LncRNA expression profiles in PBMCs of SLE patients. (A) Boxplot depicting the distribution of FPKM values for lncRNAs in each sample. (B) Volcano plot displaying the differentially expressed (DE) lncRNAs between the SLE and control groups. Each point represents a detectable gene in both groups. (C) Cluster analysis of 419 differentially expressed (DE) lncRNAs between the SLE and control groups with an adjusted p-value < 0.05. (D) Pie chart showing the number of upregulated and downregulated lncRNAs with respect to length and fold change. (E) Number of lncRNAs in different subgroups classified by fold change (FC). (F and G) Pie chart showing the classification of upregulated (F) and downregulated (G) lncRNAs including lincRNA, intronic_lncRNA, antisense_lncRNA, processed_transcript, TEC, sense_intronic, sense_overlapping, and misc_RNA. (H) Top 10 significantly upregulated or downregulated lncRNAs