Table 3 Parameters of fluorescent product generation in the real-time coumarin boronic acid assay in idiopathic inflammatory myopathies patients
From: Enhanced systemic oxidative stress response in patients with idiopathic inflammatory myopathies
Parameter | All IIM patients n = 56 | DM n = 18 | Myositis n = 38 | Control n = 50 | p-value all IIM vs. control | p-value DM vs. control | p-value myositis vs. control | p-value DM vs. myositis |
|---|---|---|---|---|---|---|---|---|
Saturating concentration (K), FLU/ml | 408.7 (337.3–636.2) | 359.8 (298.7–528.1) | 425.1 (357–766.2) | 295.3 (254.5–361.1) | < 0.001 | 0.005 | < 0.001 | 0.21 |
Velocity of fluorescent product growth (R factor), FLU/ml/min | 52.2 (42.4–80.4) | 47.2 (39.5–67.4) | 55.0 (44.5–101) | 38.5 (34.3–47.5) | < 0.001 | 0.01 | < 0.001 | 0.32 |
Cumulative in-time fluorescent product generation, FLU/ml x min | 18 703 (11 396–36 980) | 14,362 (9854–23,928) | 20,766 (11,860–42928) | 11,123 (8235–19,651) | < 0.001 | 0.27 | < 0.001 | 0.16 |