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Table 1 Demographic and clinical characteristics of the enrolled patients

From: Blood gene expression of Toll-like receptors in SLE patients with lupus nephritis or neuropsychiatric systemic lupus erythematosus

 

SLE patients

Control group

Number of patients

74

34

Age mean (min–max)

40 (19–74)

40 (24–50)

Female/Male

65/9

29/5

 

SLE (n = 74)

Duration of disease (years) mean (min–max)

11.3 (1–38)

Nonsmokers/Stop smoking/Smokers (percentage)

64.9/16.2/18.9

SLEDAI-2 K mean (min–max)

7.0 (0–43)

SLICC/ACR DI mean (min–max)

1.21 (0‒8)

C3 level (g/l) mean (min–max)

0.88 (0.2‒1.72)

C4 level (g/l) mean (min–max)

0.14 (0.06‒0.3)

 

SLE cohort

Active LN-SLE group

Inactive LN-SLE group

No LN-SLE group

Number of patients

74

11

14

47

Anti ds DNA IgG positive

46 (62.2%)

6 (54.5%)

12 (85.7%)

28 (59.6%)

Anti ds DNA IgG (IU/ml) mean when positive (min–max)

80.47 (21‒ >200)

141.3 (24‒200)

96.4 (26‒200)

91.1 (21‒200)

Anti-Smith antibody positive

16 (21.6%)

3 (27.3%)

3 (21.4%)

8 (17%)

Anti-nucleosome antibodies positive

61 (82.4%)

10 (100%)

12 (85.7%)

37 (78.7%)

Anti-nucleosome antibodies mean when positive (IU/ml) (min–max)

105.37 (1.7‒ >200)

145.3 (32‒ >200)

145.5 (46‒ >200)

122.5 (27‒ >200)

Active LN– Proteinuria (mean - g/day)

 

1.5 (0.36‒6.03)

  

Proteinuria (> 0.5 g/day)/Hematuria/Pyuria (number of patients)

 

11/4/7

  
  1. SLE Systemic lupus erythaematosus, LN lupus nephritis, TLR Toll−like receptor, SLEDAI 2 K Systemic Lupus Eryhematosus Disease Activity Index 2000, SLICC/ACR DI Systemic Lupus International Collaborating Clinics American College of Rheumatology Damage Index, C3 Complement Component 3, C4 Complement Component 4, Anti−dsDNA Anti−Double−stranded DNA Antibodies,, ACR American College of Rheumatology