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Table 1 Patient data at study enrollment and after 5 years of uveitis disease

From: Course of uveitis in children with juvenile idiopathic arthritis (JIA): Five years follow-up data from a prospective multicenter Inception Cohort of Newly diagnosed patients with JIA (ICON-JIA) study

 

Study enrollment

Initial uveitis visit

5-year uveitis FU visit

 

n = 75

n = 63a (of 75)

n = 57a (of 75)

Female, n (%)

56 (74.7%)

  

Age [y], mean (SD)

3.5 (2.1)

  

Age [y] at JIA onset, mean (SD)

3.0 (2.0)

  

Age [y] at uveitis onset, mean (SD)

4.2 (2.0)

  

Disease duration [months], mean (SD)

6.6 (5.1)

  

Interval JIA and uveitis onset [months], mean (SD)

14.4 (13.3)

  

Oligoarthritis, extended, n (%)

10 (13.3%)

  

Oligoarthritis, persistent, n (%)

42 (56.0%)

  

Psoriatic arthritis, n (%)

1 (1.3%)

  

Enthesitis-related arthritis, n (%)

1 (1.3%)

  

RF-negative polyarthritis, n (%)

18 (24.0%)

  

Other arthritis, n (%)

3 (4.0%)

  

ANA positive, n (%)

64 (85.3%)

  

HLA-B27 positive, n (%)

5 (6.7%)

  

ESR [mm/h], mean (SD)

29.2 (24.5)

20.4 (15.8)

11.1 (8.1)

CRP [mg/dl], mean (SD)

11.2 (16.8)

5.2 (7.9)

1.2 (2.1)

S100 A12 [ng/ml], mean (SD)

362.5 (547.5)

246.9 (348.5)

362.5 (547.5)

Physician’s global assessment, mean (SD)

3.6 (2.5)

2.5 (2.2)

0.9 (1.3)

Number of joints with active arthritis, mean (SD)

2.3 (2.5)

1.3 (1.8)

0.2 (0.8)

cJADAS-10, mean (SD)

8.8 (5.2)

6.7 (4.2)

2.4 (2.8)

Patient's global, mean (SD)

2.8 (2.3)

3.0 (2.4)

1.2 (1.6)

C-HAQ, mean (SD)

0.5 (0.6)

0.5 (0.7)

0.1 (0.3)

PedsQL, total, mean (SD)

72.1 (18.6)

76.9 (19.2)

88.7 (9.6)

PedsQL, physical, mean (SD)

66.2 (25.3)

74.1 (24.9)

92.1 (9.3)

PedsQL, psychosocial, mean (SD)

75.7 (16.8)

78.7 (18.1)

86.8 (12.2)

  1. JIA Juvenile idiopathic arthritis, RF Rheumatoid factor, ANA Antinuclear antibody, ESR Erythrocyte sedimentation rate, CRP C-reactive protein, cJADAS-10 Clinical Juvenile Arthritis Disease Activity Score, C-HAQ Childhood Health Assessment Questionaire, PedsQL Pediatric Quality of Life; aNumber of patients for whom the respective data were available: During the course of disease, the timepoint of arthritis and uveitis documentation might not always match. Data from the arthritis questionnaire were considered if they were documented within 30 days prior to or after the respective uveitis questionnaire