Clinical and immunological biomarkers can identify proliferative changes and predict renal flares in lupus nephritis

Table 4 Clinical characteristics of renal flares

Pts	Histological class	Type of flare Nephritic 1 Proteinuric 2	Therapy at flare	Time to renal flare months	Serum creatinine mg/dl			Proteinuria g/24H			Number of red blood cells /high power field at urinary sediment
Pts	Histological class	Type of flare Nephritic 1 Proteinuric 2	Therapy at flare	Time to renal flare months	Pre flare	At flare	At last observation	Pre flare	At flare	At last observation	Pre flare	At flare	At last observation
1	V	2	Pr. 5 mg, Tacr 3 mg, MMF 750 mg	24.0	0.68	0.71	0.80	0.34	1.6	0.13	0	0	0
2	IV	2	Pr.5 mg, MMF 1 gr	42.9	0.92	0.86	0.85	0.15	1.6	0.11	0	12	0
3	IV + V	1	Pr. 10 mg Neoral 75 mg	55.8	0.76	1.23	0.90	0.26	0.93	0.72	0	35	0
4	IV	2	Pr 6.25 mg MMF 3gr	28.7	0.85	0.9	0.95	0.24	2.3	1.20	2	7	4
5	IV	2	Pr 12.5 mg MMF 2gr	16.3	0.72	0.88	0.89	0.85	5.1	0.15	2	8	0
6	IV	1	Pr 5 mg MMF 2gr	28.1	0.65	1.1	0.70	0.18	0.9	0.05	5	20	0
7	IV + V	2	Pr 5 mg MMF 1.5gr	26.2	0.46	0.57	0.54	0.29	1.6	0.16	0	0	0
8	III + V	2	Pr 6.25 mg Tacr 3 mg	28.3	0.89	0.91	0.75	0.28	1.4	0.42	6	2	0
9	III + V	2	Pr 3.75 mg MMF 1gr	14.5	1.09	1.03	1.30	0.27	1.05	0.20	2	12	0
10	III	1	Pr 6.25 mg Neoral 100 mg	49.9	0.74	1.0	0.70	0.14	1.2	0.34	0	20	1

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