Fig. 3

Concentrations of (A-B) sphingomyelin (SM) species and (C) ceramide (Cer, HexCer) species in serum. ESI-MS/MS quantification in serum samples from controls (n = 31, blue) and early stage OA (eOA, n = 29, yellow) and late stage OA (lOA, n = 29, grey) patients. The annotation of SM species is based on the principle that 2 hydroxyl groups are attached to a sphingoid base. For more information, refer to the caption of Fig. 2. Cer, ceramide; HexCer, hexosylceramide