Table 3 Associations between SLEDAI-2 K scores or serum IFN-α concentrations and plasma NfL concentrations
SLEDAI-2 K or IFN-α variables | Estimated fixed effect | SE | T-value | p-value |
|---|---|---|---|---|
SLEDAI-2 K total | 0.015 | 0.003 | 5.0 | 1.5*10− 6 |
SLEDAI-2 K ≥ 10 (n = 28) versus < 10 (n = 171) | 0.24 | 0.04 | 5.6 | 7.2*10− 8 |
SLEDAI-2 K ≥ 4 (n = 80) versus < 4 (n = 119) | 0.095 | 0.03 | 2.9 | 0.0038 |
Anti-dsDNA and/or low complement only (n = 46) versus SLEDAI-2 K = 0 (n = 66) | 6.3*10− 3 | 0.05 | 0.13 | 0.90 |
SLEDAI-2 K arthritis (n = 18 versus n = 181) | -0.021 | 0.06 | -0.35 | 0.72 |
SLEDAI-2 K renal involvement (n = 27 versus n = 165) | 0.13 | 0.05 | 2.6 | 0.010 |
SLEDAI-2 K skin or mucosal involvement (n = 43 versus n = 156) | 0.057 | 0.04 | 1.4 | 0.17 |
LogIFN-α serum concentration | 0.047 | 0.03 | 1.8 | 0.081 |