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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Smoking as a risk factor for rheumatoid arthritis: predominant association with IgA autoantibodies – comprehensive analysis of anti-modified protein antibodies with smoking and genetic risk factors in rheumatoid arthritis

Fig. 3

Meta-analysis combining study data with SLR for the association of smoking* with ACPA-IgG and ACPA-IgA. A Meta-analysis for the association of smoking: ACPA-IgG- ACPA-IgA- versus ACPA-IgG + ACPA-IgA- B. Meta-analysis for the association of smoking: ACPA-IgG- ACPA-IgA- versus ACPA-IgG- ACPA-IgA + C. Meta-analysis for the association of smoking: ACPA-IgG- ACPA-IgA- versus ACPA-IgG + ACPA-IgA + D. Meta-analysis for the association of smoking: ACPA-IgG + ACPA-IgA- versus ACPA-IgG + ACPA-IgA +. *Smoking was defined as current versus never and past in EAC, SERA and tREACH and as ever versus never in the EIRA, TIRA- 1 and TIRA- 2. ACPA: anti-citrullinated protein antibodies. EAC: Leiden early arthritis clinic, EIRA: Epidemiological Investigations of RA [29], SERA: Scottish Early Rheumatoid Arthritis, TIRA 1: Early Intervention in RA 1, TIRA 2: Early Intervention in RA 2 [29], tREACH: treatment in the Rotterdam Early Arthritis Cohort

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Arthritis Research & Therapy

ISSN: 1478-6362

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