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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Smoking as a risk factor for rheumatoid arthritis: predominant association with IgA autoantibodies – comprehensive analysis of anti-modified protein antibodies with smoking and genetic risk factors in rheumatoid arthritis

Fig. 5

Meta-analysis combining study data with the SLR for the association of shared epitope with AAPA-IgG. A. meta-analysis of shared epitope with AAPA-IgG in all RA patients B. Meta-analysis of shared epitope in ACPA-IgG positive RA patients. AAPA: anti-acetylated protein antibodies, ACPA: anti-citrullinated protein antibodies, RA: rheumatoid arthritis; Scotland Scottish Early Rheumatoid Arthritis (SERA), Sweden: Epidemiological Investigations of RA (EIRA) [30] the Netherlands: Leiden early arthritis clinic (EAC), Canada [31], Japan [31], South Africa [31]

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