Fig. 5

Meta-analysis combining study data with the SLR for the association of shared epitope with AAPA-IgG. A. meta-analysis of shared epitope with AAPA-IgG in all RA patients B. Meta-analysis of shared epitope in ACPA-IgG positive RA patients. AAPA: anti-acetylated protein antibodies, ACPA: anti-citrullinated protein antibodies, RA: rheumatoid arthritis; Scotland Scottish Early Rheumatoid Arthritis (SERA), Sweden: Epidemiological Investigations of RA (EIRA) [30] the Netherlands: Leiden early arthritis clinic (EAC), Canada [31], Japan [31], South Africa [31]