Table 3 Ordinal logistic regression for outcome of CDAI category. This table shows unadjusted and adjusted results for ordinal logistic regression. Analysis was adjusted for age, sex, number of other IrAEs, being on steroids at time of sample, and symptom duration
Cytokine | Unadjusted OR (95% CI) | p-value | Adjusted* OR (95% CI) | p-value | |
|---|---|---|---|---|---|
IFNγ | 0.999 (0.996, 1.002) | 0.568 | 0.999 (0.996, 1.002) | 0.436 | |
IL-1 | 0.893 (0.689, 1.158) | 0.394 | 0.876 (0.666, 1.153) | 0.346 | |
IL-4 | 1.124 (0.322, 3.922) | 0.855 | 1.201 (0.326, 4.431) | 0.783 | |
IL-6 | 1.0044 (1.00007, 1.0088) | 0.046 | 1.0049 (1.00036, 1.010) | 0.035 | |
IL-10 | 1.029 (0.978, 1.083) | 0.272 | 1.041 (0.986, 1.098) | 0.146 | |
IL-12p70 | 0.884 (0.741, 1.055) | 0.173 | 0.889 (0.739, 1.069) | 0.214 | |
IL-17 A | 0.978 (0.928, 1.031) | 0.412 | 0.985 (0.930, 1.043) | 0.608 | |
TNFα | 0.994(0.981, 1.007) | 0.401 | 0.99 (0.98, 1.01) | 0.263 | |
VEGF-A | 1.0003 (1.0000, 1.0006) | 0.046 | 1.0003 (1.0000, 1.0007) | 0.032 | |