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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Bulk RNA-seq conjoined with ScRNA-seq analysis reveals the molecular characteristics of nucleus pulposus cell ferroptosis in rat aging intervertebral discs

Fig. 5

Ferroptosis-related genes and pathways are dysregulated in NP cells during IDD. A UMAP plots of NP cells subpopulations 0,4,7,8, and 13 (named subgroup-a) in 10 and 20M-old rat IVDs. B GO enrichment analysis of highly expressed genes in Group-a cells in the rat degenerative IVDs, and the top 14 biological process are shown. C Violin plot shows the expression levels of Tfrc and Fxn in 10 and 20M-old rat NP cells of subgroup-a. D Violin plot shows the expression levels of Slc3a2 and Slc7a11 in 10 and 20M-old rat NP cells of subgroup-a. E Violin plot shows the expression levels of Acsl4 and Lpcat3 in 10 and 20M-old rat NP cells of subgroup-a

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Arthritis Research & Therapy

ISSN: 1478-6362

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