Fig. 7
Cross enrichment analysis identifies the common maker of 5 ferroptotic NP cell clusters. A Scatter plot reveals the differences of genes average expression levels in rat NP cell clusters 0, 4, 7, 8 and13 (named subgroup-a) and 1, 2, 3, 5, 6, 9, 10, 11, 12 (named subgroup-b). B The top 300 in (a-b) with (a/b) > 10 genes were cross-enriched to obtain the genes highly expressed in subgroup-a (left). In addition, the top 300 in (b-a) with (b/a) > 10 genes were cross-enriched to obtain the genes that are low expressed in subgroup-a (right). C Heat map shows the average expression levels of the genes obtained by enrichment analysis in the cell subsets of subgroup-a and subgroup-b. D Violin plot shows the expression levels of Cxcl1 and Rps6 in rat IVD NP cell subsets of group-a and subgroup-b. E UMAP plots of Cxcl1 and Rps6 expression distribution in NP cell subsets