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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: The T-cell response to SARS-CoV- 2 vaccination persists beyond six months in rheumatoid arthritis patients treated with rituximab

Fig. 1

Spike-specific T-cell response in the study cohort. Blood samples from patients with RA not treated with RTX (RA no RTX, n = 24) or treated with RTX (RA RTX +, n = 51) were analyzed by flow cytometry after spike peptide activation. Stimulation indexes (Stim Index) were calculated as ratios between spike activation and negative condition percentages. The data are given for either CD69 + CD154 + or CD69 + CD137 + or CD69 + CD107a + or CD154 + CD137 + or CD154 + CD107a + or CD137 + CD107a + CD4+ T cells (A) or CD8.+ T cells (B) and were compared between both groups. Green symbols (circles in the RA without RTX group and triangles in the RA RTX + group) refer to vaccinated patients who had no history of COVID- 19. Red symbols (circles in the RA non-RTX group and triangles in the RA RTX + group) refer to vaccinated patients who had a history of COVID- 19

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Arthritis Research & Therapy

ISSN: 1478-6362

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